A limited set of actions can assigned via macro commands. Incompatible actions are ommited from the generated macro. Also note that Macros are limited to 15 lines each.
Patch 6.3 lvl 80
Patch 6.3
Personal Hotbar Setup
Core / Frequent Action items focused on Hotbar 1 (ST 1-6 & AoE 7-12) Secondary Actions/Buffs/Debuffs found on Hotbars 2 and 3
Usage
Maiming.