A limited set of actions can assigned via macro commands. Incompatible actions are ommited from the generated macro. Also note that Macros are limited to 15 lines each.
This layout is designed around the following hardware:
Key: ^ - Control, * - Shift
comfy layout with the reawaken combo made easier
panels for MMO mouse with 2 3x4 hotbars and 1 6x2 for utility
fits all actions for more comfortable combo rotations and movement while fitting all role actions, LB, and sprint and some free slots on the WXHB for extra stuff (mounts, items, etc)
2 is for AOE combo > stays at the top 1 is for Standard combo (single target) > main bar 3 is for Role skills