A limited set of actions can assigned via macro commands. Incompatible actions are ommited from the generated macro. Also note that Macros are limited to 15 lines each.
1st: 1,2,3,4,5,Q,E,R,F,C,V,T 2nd: same but shift+
I'm a left arm amputee - for 1-handed MMO mouse use (Logitech G600).
Tweaked the layout that got me from 80-90, still a work in progress.
Right side of LT/RT for instant cast actions, to make movement easier. Left side for things with cast timers and Scenic Muse, which has a long cooldown.
RT, RT for actions that are us
tentative pct xhb layout, 3rd bar is both triggers, i have either combination go to the same hotbar