A limited set of actions can assigned via macro commands. Incompatible actions are ommited from the generated macro. Also note that Macros are limited to 15 lines each.
Layout created by the YouTuber Squintina https://www.youtube.com/watch?v=s3LA7ap4gM0 with some adaptations.
Nascente Flash Macro :
/merror off
/ac "Nascent Flash" <2>
/ac "Nasc
PLD
First version of Azeron layout. Hotbar 3 is center row of buttons, 1 & 2 are upper flick buttons, 4 & 5 are squeeze buttons. Actions on the upper halves of hotbars are shift (nub click) + 1-4 (pinky-pointer). Hotbar 4 sides are shift and outer buttons.
Bunboss https://www.youtube.com/watch?v=Mf5pTbncRKo
Main tank. Adapted for XIVcombo.