Maybe this hotbar will make me like playing DRG more. I've now come to accept that the AoE combo will have to sit away from the first hotbar.

Note: I haven't really tried this yet. Will update if needed.

Hotbar 1: GCD combo & frequent oGCDs.
Starting from the top center, then the combos branch off to the side and down, before crossing over. I've always had my position as flank left, rear right, even if it makes the SAM UI awkward with the glowy stickers mirrored. If and when I decide to let go of the custom of leaving Sprint where it is by default, that would be where I'd put True North.

Hotbar 2
-First row, we have the AoE 1-2-3.
-Second row houses the gap closers. All my applicable job hotbars put the gap closer in the middle, so that's where the damage-less gap closer goes since it's for mobility. The other two shouldn't be used for mobility anyway, so the gap closer row thing is just coincidental.
-Third row: That's just where I usually put my Second Wind, and gap-widener. As for Lance Charge, I thought I'd let it be vertical neighbours with the 2-minute burst buff action.
-Fourth row: For bloodbath and the 2-minute burst buff, that's just where I usually put them for all applical jobs. I also usually put the ranged action two spots above, but since it's really low priority for melee jobs, it's not a big deal to be pushed down to the corner.

Hotbar 3:
Yup, just more of my personal template for all jobs, or those within the role. I don't usually put True North on the third hotbar, but with Dragoon's very busy hotbar, that's just where I'll have to put it. As I mentioned, if I'm willing to part ways with leaving Sprint in its default position, TN would definitely take that spot.

DRG MMO mouse hotbar setup, Dawntrail v1

boatium

I only really started taking the layout seriously after DT released. 

This setup omits collectable items. I find it's more of a necessity on controller/XHB, so it'll be on that.

Hotbar 1: Actions that I would actually use. The first row becomes obsolete once you hit certain stats but I just like keeping it there. 

Hotbar 2: Actions that I don't see myself using, or that I haven't looked up when a good time is to use them. The exception is the switch to MIN/BTN.

Hotbar 3: Toggles that are normally useless but are needed in case you misclick your buffs. The 0 is the placeholder for a mount. If using mount roulette, use favourites that don't include mounts that replace the first hotbar if you have it set like that.

Teleport, return, and materia extraction are on my shared hotbar 4.

BTN/MIN (MMO Mouse)

Note: I haven't leveled this up to 100 yet.

Hotbar 1: Starting with the single target filler, regen, and DoT on the first row. Next row has the WHM-specific actions. The rest is the same: heal, weak AoE heal (in case of sync-down), esuna, zoomies, weak heal (ONLY for sync-downs that the normal heal isn't there), sprint.

Hotbar 2 (ctrl): As usual, first row is the AoE hitter, bubble, and 3-in-1 AoE. oGCDs along the left side, then the heal-harder button. The dash forward being a new addition just has to be added to my usual hotbar spot for it. Below are the AoE regen, and the beeg AoE heal. Legacy hotbar positions for sleep and lucid from my SMN sprout days. While WHM doesn't have a buff team DPS button, Temperance goes there because similar to AST, at level 100, it'll turn into a follow-up action.

Hotbar 3 (shift): Usual spots for surecast, swiftcase, raise, rescue. Top row has the WHM-unique actions: healing flower thing, and hard hitter after spending three other things. Then leftover spots on the left are tank assists.

Personal MMO Mouse WHM

Hotbar 1: My healers tend to follow this format, with the exception being Sage of course.

Row 1: Single target, regen, DoT
Row 2: The job specific goodies. These are three cards.
Row 3: Stronger heal, weak regen (in case of roulette sync), esuna
Row 4: Zoomies, weak heal (in case of roulette sync), sprint.

Hotbar 2 (ctrl): I tend to put the AoE attack in this corner, then the bubble, then some sort of special AoE. Down along the left side tends to be my two oGCD heals, then the "cure harder" button. Down the middle would be two job-special AoEs, then the "turn regens into shields" button. Down along the right side, these are carry-overs from my SMN sprout days: sleep, lucid dreaming, team DPS buff.

Hotbar 3: Let's begin with the legacy carry-overs from my sprout SMN hotbar - surecast, swiftcast and raise. I also like to see LB as an advanced raise so it gets to stay on that row too. The leftover spots on the left side tend to be the tank assists. I'm not sure where else macrocosmos can be swapped in to so I've left it here. It's not used that often either.

Personal MMO Mouse AST

Hotbar 1: The good ol 1-2-3 combo on top, then the single + AoE oGCDs along the right side, then the legacy spot for Sprint. Next row down is AoE 1-2 combo. Then next row is the ranged and gap close, which thankfully still works as a free damage button in 7.0. Then the two bursties.

Hotbar 2 (ctrl): A few oddities in here. Top left is the burst hitter. Next is technically the alternative 3 in the 1-2-3 combo, since it felt more fluent to press 1, 2, ctrl+2. Next is the single-target spender.  This was just built on the rotations as I leveled up and placed these actions accordingly. On row 2, bloodwhetting and the AoE spender just had to be neighbours. Row 3 has the job-specific mitigations, although now that I re-read the tooltip, Thrill and Bloodwhetting could be great vertical neighbours. Row 4 has the straight up heal, low recast time shield-a-friend, and team shield. 

Hotbar 3: Same as usual with all my tanks.

Personal MMO Mouse WAR

Hotbar 1: Similar format based on my first tank (GNB). 1-2-3 combo on top. MP-spending oGCDs along the right side. Next row is the AoE 1-2 combo. Then the ranged and gap closer. Then the "bursts" for DRK, and lastly, the grandfathered seat for Sprint.

Hotbar 2 (ctrl): Looking at the first 2x2, single target on top, AoE on bottom; GCD/gauge spenders left, oGCDs middle. Then we have the odd one out, the AoE puddle of hurties. Rampart and reprisal are where they are for all my tanks. Third row also has the job-specific overall high mitigation, then the specific mitigation (DRK is magic, while GNB is phys). While DRK doesn't have a plain heal button, TBN is as close as it gets. While this one has a 60s recast, I decided Oblation gets to take this one for having two charges and can be put on a teammate. Bottom right is the team mitigation.

Hotbar 3 (shift): Same format, except the phone a friend button gets its own little corner, since I've run out of space on the other two hotbars.

Personal MMO Mouse DRK

This was my first tank job that I actually worked on, and paved the way for all my other tank jobs to use a similar setup.

Hotbar 1: On top there's the 1-2-3 combo. Along the right side down, there's the oGCD, and AoE oGCD. Second line is the AoE 1-2 combo. 3rd row is the ranged action and gap closer. Last, there's the two burst window related actions - the hit-harder button, and the free cartridges button. And the sprint has always been there for all the jobs. Sprout carryover.

Hotbar 2 (ctrl): Top rows, tank-specific DPS zone. Then Rampart and Reprisal are where they are for all my tank jobs. The rest of the 3rd row is for the job specific mitigations. Last row generally begins with a heal, a quick-recharge mitigation button, and a team mitigation.

Hotbar 3 (shift): This becomes the template to be used for all my tank hotbars. Fillers in empty spaces include emotes, mounts, food/potions. 

Personal MMO Mouse GNB

Hotbar 1: White mana on the left side, black mana on the right side. Single target above, AoEs below. Both/neutral down the middle. I used to put acceleration on Hotbar 3, but it's better this way for quick succession to the relevant actions.

Hotbar 2 (ctrl): The 1-2-3 melee combo on top. I usually have my gap close/make on those two middle positions. Sleep, lucid, cure, and the DPS buff are just rollovers from my old hotbar as Summoner, my first job, and that was before I put more thought into hotbar setups. AoE and run+gun spenders on the bottom row.

Hotbar 3 (shift): Surecast, team mitigations, swiftcast, LB and raise tend to be in these positions across all my jobs. The numbers are fillers, like the /pet emote for petting G'raha Tia, some dance emote, super-ethers/potions, mounts.

Personal MMO Mouse RDM

Now that I've actually tried controller fishing for a bit, this is how it's sorted.

XHB1 RT/RH: Actions here are grouped together for simple line fishing that does not involve mooching. 

XHB1 RT/LH: Patience is put here for its quick access to cast line immediately after. I haven't found myself needing to use double/triple hook yet, so this might be moved later on?

XHB1 LT/LH: The hookset and mooch actions are moved here to allow one-handed gameplay due to how often these are used. 

XHB1 LT/RH: Things I don't use too often.

The WXHBs are things like toggles, things used in between fishing sessions, things not used that often. 1/2 are placeholders for cordials, 3 for food. Cordials may be moved to XHB1, most likely swapping places with double/triple hook, since I feel like I'd have to really intend and plan to use those.

For XHB3, that's spear fishing. No need to have quick access to it. Just swap hotbars if I'm going spearfishing lol.