I created my chotbars to be comfortable, practical, and aesthetic.(to me anyway) Nearly all same/similar skills are in the same position across all jobs/roles while allowing for as little finger gymnastics as possible.

My XHB is split between chotbars 2(left) and 7(right)

DPS Icon 1 = Last Dance

I show Cross Hotbar 3 (Left) with both of the expanded trigger controls, so you can easily add in another 8 actions if you prefer, I use XHB 8 as a shared bar between all classes for traversal and general actions outside of combat. Role actions are consistent among my layouts, and so are general actions. The macro icon is a placeholder for a Tincture/Gemdraught.

for each job, I create a "hotbar" that is basically a monitor for any spell/skill/cooldowns I want to see the status of; I also have a hotbar with Role spells & skills, and, Sprint. These are the spells I have for Dawntrail. I use Hotbars 2 & 10 but you can use any Hotbars you want.

Bar 1: single target Bar 2: AOE Bar 3: XHB

Valen Bree

WIP with aoe abilities on the extended XHB

Puts most of the strain on the left hand, and off of the right.

Single Target (L)

Mobs (R)

Endwalker Lvl90 Dancer

Single target on right, AOE on left, dances and buffs on cross.

MMO mouse setup with modifiers.